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All patients hospitalized with new or relapsing neurologic events after SARS-CoV-2 vaccination at a New York tertiary hospital had one or more risk factors for their neurologic condition, a prospective study showed.

The most prominent neurologic index events in these vaccinated patients were ischemic stroke (37.7%), encephalopathy (32.6%), seizure (15.9%), and intracranial hemorrhage (ICH; 9.4%), according to Kiran Thakur, MD, of Columbia University Irving Medical Center/NewYork-Presbyterian Hospital in New York City, and co-authors.

Of 3,830 individuals screened from December 2020 through June 2021 for COVID-19 vaccination status and neurologic conditions, 138 had a neurologic differential diagnosis and a COVID vaccine within 6 weeks of hospitalization, including 126 who received an mRNA vaccine. All 138 cases had at least one risk factor or evidence of a known potential cause of their neurologic event, Thakur and colleagues reported in Neurology: Clinical Practice.

Metabolic derangement was the most common etiology for vaccinated patients with seizures (53.3%) and encephalopathy (22.7%). Hypertension was the most significant risk factor for those with ischemic stroke (86.5%) and ICH (30.8%). Head over to MedPage Today to read more about it.